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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RSPO4
All Species:
19.7
Human Site:
T121
Identified Species:
48.15
UniProt:
Q2I0M5
Number Species:
9
Phosphosite Substitution
Charge Score:
0.33
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q2I0M5
NP_001025042.2
234
26171
T121
Y
K
G
K
C
L
P
T
C
P
P
G
T
L
A
Chimpanzee
Pan troglodytes
XP_525242
237
25852
T98
Y
K
G
K
C
L
P
T
C
P
P
G
T
L
A
Rhesus Macaque
Macaca mulatta
XP_001112556
172
19602
E84
Y
F
G
I
R
G
Q
E
V
N
R
C
K
K
C
Dog
Lupus familis
XP_542937
213
23912
T102
Y
K
G
K
C
L
P
T
C
P
L
G
T
A
A
Cat
Felis silvestris
Mouse
Mus musculus
Q8BJ73
228
25847
S121
Y
K
G
K
C
L
P
S
C
P
P
G
T
L
T
Rat
Rattus norvegicus
XP_575261
228
25872
T121
Y
K
G
K
C
L
P
T
C
P
P
G
T
L
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517935
235
25876
E99
H
R
G
R
C
F
D
E
C
P
D
G
F
A
P
Chicken
Gallus gallus
XP_418383
230
25958
G116
H
R
G
R
C
F
R
G
C
P
P
G
F
A
A
Frog
Xenopus laevis
Q5UE90
243
27861
E127
L
K
G
Q
C
F
E
E
C
P
E
G
F
A
P
Zebra Danio
Brachydanio rerio
Q6DHR0
261
29032
S129
H
R
G
R
C
F
S
S
C
P
E
G
F
T
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
76.3
72.2
78.6
N.A.
81.6
82
N.A.
40
38
39.9
35.2
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
79.3
72.6
82.9
N.A.
88.4
88.8
N.A.
57
55.5
59.2
52.8
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
13.3
86.6
N.A.
86.6
93.3
N.A.
33.3
46.6
40
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
13.3
86.6
N.A.
93.3
93.3
N.A.
53.3
66.6
46.6
60
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
40
40
% A
% Cys:
0
0
0
0
90
0
0
0
90
0
0
10
0
0
10
% C
% Asp:
0
0
0
0
0
0
10
0
0
0
10
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
10
30
0
0
20
0
0
0
0
% E
% Phe:
0
10
0
0
0
40
0
0
0
0
0
0
40
0
0
% F
% Gly:
0
0
100
0
0
10
0
10
0
0
0
90
0
0
0
% G
% His:
30
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
60
0
50
0
0
0
0
0
0
0
0
10
10
0
% K
% Leu:
10
0
0
0
0
50
0
0
0
0
10
0
0
40
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
50
0
0
90
50
0
0
0
20
% P
% Gln:
0
0
0
10
0
0
10
0
0
0
0
0
0
0
0
% Q
% Arg:
0
30
0
30
10
0
10
0
0
0
10
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
10
20
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
40
0
0
0
0
50
10
20
% T
% Val:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
60
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _